RNAi vector and its application
Title：
RNAi vector and its application
Application Number：
 200710099146
Application Date：
 2007/05/14
Announcement Date：
 2007/11/07
Pub. Date：
Publication Number：
 101067139
Announcement Number：
Grant Date：
Granted Pub. Date：
ApplicationType：
 Invention
State/Country：
 94[China|shenzhen]
IPC：
 C12N 15/86A61K 48/00
Applicant(s)：
 Shenzhen Graduate School, Tsinghua Univ.
Inventor(s)：
 Yang Zhengrong, Huang Laiqiang, Wang Haifeng
Key Words：
 RNAi vector, application
Abstract：
 The present invention discloses one kind of RNAi vector and its application, and provides one kind of recombinant SFV expression vector based on SFV virus replicon vector and its application in preparing treating medicine for inhibiting the target gene expression. The RNAi vector is recombinant SFV expression vector with SFV vector skeleton containing CMV IE promoter and Sv40 poly A, the CMV IE promoter has GenBank number of U57607.1(1-589), and Sv40 poly A has GenBank number of AM697713(2404-2644). The vector is suitable for use in research needing short time and high efficiency silence of target gene, especially in preparing treating gene medicine for inhibiting target gene expression. Therefore, the present invention is significant in biomedicine and gene function research.
Claim：
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