The present invention relates to a method for removing radionuclide ions from water containing radioactive substance. It is characterized by that between anode and cathode several units are arranged, every unit is formed from anionic-cationic exchange membranes and anionic-cationic exchange resin filled between anionic-cationic exchange membranes, the described filled resin is styrene-divinylbenzene resin with the characteristics of large exchange capacity, high conversion rate, uniform particle size, low dissolubility in hot water and radiation resistance. Said invention can utilize the ion exchange resin to adsorb the radionuclide ions in the water so as to attain the goal of said invention.