Thiophosphamino acid ester compound containing 3''-azido-deoxythymidine and its preparing process
Title：
Thiophosphamino acid ester compound containing 3''-azido-deoxythymidine and its preparing process
Application Number：
 01130786
Application Date：
 2001/08/24
Announcement Date：
 2002/04/10
Pub. Date：
Publication Number：
 1343673
Announcement Number：
 1133641
Grant Date：
Granted Pub. Date：
 2004-1-7
ApplicationType：
 Invention
State/Country：
 11[China|beijing]
IPC：
 A61P 31/12, A61P 31/18, A61P 35/00, C07H 19/06, C07H 19/10
Applicant(s)：
 Qinghua Univ
Inventor(s)：
 Zhao Yufen, Miao Zhiwei, Fu Hua
Key Words：
 Thiophosphamino acid ester compound, 3''-azido-deoxythymidine, preparing process
Abstract：
 A thiophosphamino acid ester compound containing 3'-azido-deoxythymidine is prepared through dissolving (aryl substituted) dichlorothion in tetrahydrofuran (THF), adding amino acid methylester hydrochloride, adding acid capturing agent, adding solution of 3'-azido-deoxythymidine, adding acid capturing agent, filter, rotary distillation and chromatography. The said compound has anti-AIDS activity.
Claim：
Priority：
PCT：
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