Metal surface constructional gradient biological layer and its preparation and usage |
Title： |
| Metal surface constructional gradient biological layer and its preparation and usage |
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Application Number： |
200410000725 |
Application Date： |
2004/01/16 |
Announcement Date： |
2004/12/29 |
Pub. Date： |
2007/11/07 |
Publication Number： |
1557505 |
Announcement Number： |
100346845 |
Grant Date： |
2007-11-7 |
Granted Pub. Date： |
2007-11-7 |
ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
A61L 27/32, A61L 27/06, C25D 9/04 |
Applicant(s)： |
Tsinghua University |
Inventor(s)： |
Zhang Renji, Tang Guangxin, Yan Yongnian |
Key Words： |
Metal surface constructional, gradient, biological layer, preparation, usage |
Abstract： |
The present invention relates to composite oxidation process for surface modification of metal. The composite oxidation process includes first anode oxidation to from compact anatase titania film on the surface of substrate, then micro arc oxidation to form porous calcium and phosphorus containing anatase or mixed anatase-rutile titania coating on the surface of the film. The coating substrate is titanium or titanium alloy and the coating is one gradient structure comprising inner compact layer and surface porous uneven layer. Clinical practice shows that the compact titanium film can inhibit effectively the leaching out of harmful metal ion to body fluid, the surface porous structure is favorable to the growth of bone tissue, the adhesion between the bone tissue and the implant and the cell proliferation, and the calcium and phosphorus elements are favorable to forming bone-like hydroxyapatite in body fluid. |
Claim： |
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Priority： |
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PCT： |
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LegalStatus： |
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