Constructing method for candida tropicalis gene engineering recombinant bacterium
Title：
Constructing method for candida tropicalis gene engineering recombinant bacterium
Application Number：
 200410096698
Application Date：
 2004/12/07
Announcement Date：
 2005/05/11
Pub. Date：
Publication Number：
 1614004
Announcement Number：
Grant Date：
Granted Pub. Date：
ApplicationType：
 Invention
State/Country：
 11[China|beijing]
IPC：
 C12N 1/19, C12N 15/63, C12N 15/66, C12N 15/81, C12N 15/54
Applicant(s)：
 Tsinghua Univ.
Inventor(s)：
 Cao Zhu''an, Gao Hong, Hua Yutao
Key Words：
 Constructing method, candida tropicalis, gene engineering, recombinant bacterium
Abstract：
 This invention relates to a construction method of tropic Candida gene engineering strain. Initial strain is product strain for industry, blocking one copy gene of carnitine acetyl CoA CAT and constructing a gene engineering recombination strain. At the same conditions, growth state of initial and recombination strain are same. CAT enzyme activity of recombination strain drops to half of that of initial strain. Speed rate of producing acid is improved. Crop of dibasic acid and percent conversion increases obviously.
Claim：
Priority：
PCT：
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2008-4-17
  Selected patents owned by Tsinghua University filed in 2005 are loaded.
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