Polypeptide compound with aza-containing heterocyclic modified and its application
Title：
Polypeptide compound with aza-containing heterocyclic modified and its application
Application Number：
 200710062628
Application Date：
 2007/01/11
Announcement Date：
 2007/07/18
Pub. Date：
Publication Number：
 100999546
Announcement Number：
Grant Date：
Granted Pub. Date：
ApplicationType：
 Invention
State/Country：
 11[China|beijing]
IPC：
 C07K 7/06A61K 47/48A61K 38/08A61P 25/28A61P 3/10
Applicant(s)：
 Tsinghua Univ.
Inventor(s)：
 Li Yanmei, Wu Weihui, Lei Peng, Su Xiaoyang, Hu Jia
Key Words：
 Polypeptide, compound, aza-containing heterocyclic, modified, application
Abstract：
 The present invention discloses one kind of nitrogen heterocycle modified polypeptide compound and its application in preparing medicine for preventing and treating Alzheimerdis, Parkinson''s disease and other degenerative nerve system diseases and medicine for preventing and treating type II diabetes. Research shows that the nitrogen heterocycle modified polypeptide compound can inhibit Abeta aggregation, disaggregate Abeta, hydrolyze to eliminate Abeta protein and inhibit and eliminate Abeta toxicity, and possesses wide application foreground in pharmaceutical field.
Claim：
Priority：
PCT：
LegalStatus：

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2008-4-17
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