Expression vector for siRNA of mammal cell
Title:
Expression vector for siRNA of mammal cell
Application Number:
200310117340
Application Date:
2003/12/10
Announcement Date:
2005/06/15
Pub. Date:
2006/08/16
Publication Number:
1626663
Announcement Number:
1269962
Grant Date:
2006-8-16
Granted Pub. Date:
2006-8-16
ApplicationType:
Invention
State/Country:
11[China|beijing]
IPC:
C12N 15/85C12N 15/11C12N 5/10
Applicant(s):
Tsinghua Univ.
Inventor(s):
Zhang Shuping, Chang Zhijie, Fu Xinyuan
Key Words:
Expression vector, siRNA, mammal cell
Abstract:
A mammal cell siRNA expression carrier existing in linear state is composed of two or three LoxP sites, the neomycin resistance gene controlled by the promoter of murine phosphoglycerate kinase gene, promoter U6 and two viscose terminals. It can be used to create the staible siRNA expression cell line of mammal and the gene silencing mouse model for silencing gene and restoring the silenced gene.
Claim:
Priority:
PCT:
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  Selected patents owned by Tsinghua University filed in 2005 are loaded.
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