Compound of pyrazole [4,3-c] quinolines and preparation process thereof
Title:
Compound of pyrazole [4,3-c] quinolines and preparation process thereof
Application Number:
200410004444
Application Date:
2004/02/23
Announcement Date:
2005/01/05
Pub. Date:
2006/05/24
Publication Number:
1560054
Announcement Number:
1257168
Grant Date:
2006-5-24
Granted Pub. Date:
2006-5-24
ApplicationType:
Invention
State/Country:
11[China|beijing]
IPC:
C07D 471/04, C07D 221/00, C07D 231/00
Applicant(s):
Tsinghua Univ.
Inventor(s):
Qiao Renzhong, Zhao Yufen
Key Words:
pyrazole [4,3-c] quinolines, preparation process
Abstract:
The invention discloses a parazole [4, 3-c] quinoline compound and its preparing method. It is 3-amino-6/8 substituted-1H-parazole [4, 3-c] quinoline compound. The preparing method includes the steps: 1) preparing 3-aryl-6-(6-/8-substituted-4-chloroquinoline-3-radical)-1, 2, 4-triazolo[3, 4-c]-1, 3, 4-thiadiazole; 2) dissolving the product prepared in step 1) in anhydrous alcohol in molar ratio of 1 to 3-6, heating and returning at 78-85 deg.C until it disappears, so as to obtain a deposit, namely the parazole [4, 3-c] quinoline compound.
Claim:
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