Compound of poly-amide macrocyclic polyamine and its preparation process and application |
Title： |
| Compound of poly-amide macrocyclic polyamine and its preparation process and application |
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Application Number： |
200410004532 |
Application Date： |
2004/02/20 |
Announcement Date： |
2005/01/05 |
Pub. Date： |
2006/06/07 |
Publication Number： |
1560053 |
Announcement Number： |
1258532 |
Grant Date： |
2006-6-7 |
Granted Pub. Date： |
2006-6-7 |
ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
C07D 403/14, C07F 1/08, C07F 3/06, C07F 5/00, C07H 21/00, C07D 207/34, C07D 257/02 |
Applicant(s)： |
Tsinghua Univ. |
Inventor(s)： |
Zhao Yufen, Qiao Renzhong, Yu Xiaoqi |
Key Words： |
poly-amide macrocyclic polyamine, preparation process, application |
Abstract： |
The invention discloses a polyamide large-ring polyamine compound and its preparing method and application, providing a polyamide large-ring polyamine compound and its preparing method as well as a nucleic acid cutting reagent using its metal complexes as active components. The polyamine compound is N-(-(4-(4-(4-(N-methyl pyrrole-2-acyl)amino-N-methyl pyrrole-2-amino)amino-N-methyl pyrrole-2-acyl)amino-N-methyl pyrrole-2-acyl)amino-butyric acid-1,4,7, 10-tetraazacyclododecane. It also provides a preparing method and a nucleic acid cutting reagent using the metal complexes of the polyamine compound as active component. The invention provides a good foundation and effective way for further synthesizing DNA fixed-point identifying and cutting reagent, and has important significance. |
Claim： |
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Priority： |
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PCT： |
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LegalStatus： |
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