High-sensitivity surface plasma resonance detector with multiple total reflection |
Title: |
High-sensitivity surface plasma resonance detector with multiple total reflection |
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Application Number: |
200310100368 |
Application Date: |
2003/10/14 |
Announcement Date: |
2004/09/15 |
Pub. Date: |
2006/03/22 |
Publication Number: |
1529147 |
Announcement Number: |
1246686 |
Grant Date: |
2006-3-22 |
Granted Pub. Date: |
2006-3-22 |
ApplicationType: |
Invention |
State/Country: |
11[China|beijing] |
IPC: |
G01N 21/21G01N 21/41G01N 21/55 |
Applicant(s): |
Tsinghua Univ. |
Inventor(s): |
Bao Junbo, Wang Juying, Liu Litian |
Key Words: |
High-sensitivity, plasma, resonance detector, total reflection, multiple |
Abstract: |
The invention relates to optical testing instruments. Metallic thin film as sensing film is prepared on plane above a cylindrical mirror, photoelectric detector is under the cylindrical mirror, and incident light source is at left side. Occurred multiple times inner total reflections of light from source through cylindrical mirror irradiating between the cylindrical mirror and metal thin film make changes of light intensity of refracted light path and emergent light path take place simultaneously. Comparing with traditional inner total reflection of simple point, the invention raises sensitivity and signal resolution for detecting vibrator resonance of plasma on surfaces since tested molecules of specimen absorb the said changes of light intensity fixed on the film. The invention can monitor interreaction between molecules in real time and on site, and is applicable to researches in chemistry, biochemistry, biotechnology, molecular biology and microbiology etc. |
Claim: |
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Priority: |
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PCT: |
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LegalStatus: |
2007-12-12Date of termination due to fee |