Preparation method of nanometer phase calcium-phosphorus salt/collagen/polylactic acid bone composite material |
Title： |
| Preparation method of nanometer phase calcium-phosphorus salt/collagen/polylactic acid bone composite material |
|
Application Number： |
00107493 |
Application Date： |
2000/05/19 |
Announcement Date： |
2000/11/08 |
Pub. Date： |
|
Publication Number： |
1272383 |
Announcement Number： |
1106861 |
Grant Date： |
|
Granted Pub. Date： |
2003-4-30 |
ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
A61L 27/56 |
Applicant(s)： |
Qinghai Univ. |
Inventor(s)： |
Cui Fuzhai, Cai Qiang, Zhang Shuming |
Key Words： |
nanometer phase calcium-phosphorus salt, collagen, polylactic acid bone, composite material |
Abstract： |
The present invention relates to a preparation method of nanometer phase calcium-phosphorus salt/collagen/polylactic acid bone composite porous material, including the following steps: drip-adding H3PO4 into collagen solution, making CaCl2.6H2O dissolve in deionized water, and drip-adding it into the above-mentioned solution, then drip-adding NaOH solution to make pH value be 6-8, adding solvent into polylactic acid to obtain homogeneous solution, then adding calcium-phosphorus salt powder material, finally making polylactic acid/calcium-phosphorus salt/collagen into the composite porous material, and then making the composite porous material undergo the processes of thermal phase-separation and subsequent sublimation of solvent so as to obtain the said invented product with a lot of communicated micropores, good strength and biocompatibility. |
Claim： |
|
Priority： |
|
PCT： |
|
LegalStatus： |
|
Relevancy information
