Medicine for treating AIDS and its preparing method
Title:
Medicine for treating AIDS and its preparing method
Application Number:
00123483
Application Date:
2000/08/18
Announcement Date:
2002/03/13
Pub. Date:
Publication Number:
1339318
Announcement Number:
1172717
Grant Date:
2004-10-27
Granted Pub. Date:
2004-10-27
ApplicationType:
Invention
State/Country:
11[China|beijing]
IPC:
A61K 39/395, A61P 31/18
Applicant(s):
Qinghua Univ.
Inventor(s):
Chen Yinghua, Xiao Yi, Tian Haiyun
Key Words:
Medicine, treat, AIDS, preparing method
Abstract:
The AIDS treating medicine of the present invention includes at least a kind of monoclonal antibody, the antigen of which is ELDKWA neutralizing epitope and its variation epitopes ELEKWA, ELNKWA and ELDEWAF of human immune deficiency virus transmembrane protein gp41. It is prepared through the steps of: artificial synthesis of at least one polypeptide containing ELDKWA neutralizing epitope and/or its variation epitopes of human immune deficiency virus transmembrane protein gp41; coupling the said polypeptide to carrier protein or carrier polypeptide; immunizing animal with the said conjugate; preparing hybrid tumor; and compounding the obtained antibody with medicinal adjuvant to obtain the medicine.
Claim:
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PCT:
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2008-4-17
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