Nucleoside 5''-thiophosphoryl amino-acid ester compound
Title：
Nucleoside 5''-thiophosphoryl amino-acid ester compound
Application Number：
 00129555
Application Date：
 2000/10/09
Announcement Date：
 2001/04/11
Pub. Date：
Publication Number：
 1290707
Announcement Number：
 1133642
Grant Date：
Granted Pub. Date：
 2004-1-7
ApplicationType：
 Invention
State/Country：
 11[China|beijing]
IPC：
 C07H 19/20
Applicant(s)：
 Qinghua Univ.
Inventor(s)：
 Zhao Yufen, Miao Zhiwei, Han Bo
Key Words：
 Nucleoside 5''-thiophosphoryl amino-acid ester
Abstract：
 Nucleoside 5'-thiiophosphoryl amino acid ester compound is prepared through the processes of dissolving thiophosphoryl trichloride in dried tetrahydrofuran, addition of carbamate hydrochloride through stirring, dripping acid binding agent to react, filtering, rotating distillation to eliminate solvent and other low boiling point matters, hydrolysis in ammonia water and final silica gel chromatography. The compound of the present invention may be used in developing medicine with antiviral, antitumor and HIV resisting activity.
Claim：
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PCT：
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2008-4-17
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