Compound of styryl with axa-containing heterocyclic modified and use thereof |
Title： |
| Compound of styryl with axa-containing heterocyclic modified and use thereof |
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Application Number： |
200710062629 |
Application Date： |
2007/01/11 |
Announcement Date： |
2007/07/18 |
Pub. Date： |
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Publication Number： |
100999495 |
Announcement Number： |
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Grant Date： |
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Granted Pub. Date： |
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ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
C07D 225/02C07C 229/16C07C 237/06A61K 47/48A61K 31/19A61K 31/665A61K 31/216A61P 25/28A61P 25 |
Applicant(s)： |
Tsinghua Univ. |
Inventor(s)： |
Li Yanmei, Wu Weihui, Lei Peng, Su Xiaoyang, Hu Jia |
Key Words： |
Compound of styryl, axa-containing heterocyclic, modified |
Abstract： |
This invention relates to an azacyclo-modified styrene compounds and its applications. Its purpose is to provide an azacyclo-modified styrene compounds, and its applications in the preparation of Alzheimer''s disease, Parkinson''s disease and other degenerative nervous system disease or type two diabetes prevention and therapeutic drug. Studies show that the invention can inhibit aggregation of A beta, also can make the A beta aggregate depolymerizate, and will eventually hydrolysis and eliminate A beta protein, inhibited and removal of A beta toxicity, in the field of medicine has broad application prospects. |
Claim： |
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Priority： |
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PCT： |
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LegalStatus： |
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