Process for producing 1,3-propylene glycol by microorganism aerobic fermentation |
Title： |
| Process for producing 1,3-propylene glycol by microorganism aerobic fermentation |
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Application Number： |
200510086677 |
Application Date： |
2005/10/20 |
Announcement Date： |
2006/04/26 |
Pub. Date： |
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Publication Number： |
1763210 |
Announcement Number： |
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Grant Date： |
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Granted Pub. Date： |
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ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
C12P 7/18 |
Applicant(s)： |
Tsinghua University |
Inventor(s)： |
Liu Dehua, Liu Hongjuan, Hao Jian, Lin Rihui |
Key Words： |
microorganism, aerobic fermentation, 1,3-propylene glycol, producing process |
Abstract： |
The present invention provides microbial aerobic fermentation process of producing 1, 3-propylene glycol, and belongs to the field of biochemical technology. Seed liquid is first added into industrial glycerin or initial fermentation culture medium of glycerin fermenting liquid with glycerin concentration of 20-50 g/L, and under fermentation condition of 30-40 deg.c, the culture medium is fermented with PDO producing Klebsiella pneumoniae or acid producing Klebsiella pneumoniae to produce PDO. During fermentation, air in 0.2-1.0 vvm is led in, the fermented matter is stirred in 50-250 rpm, glycerin and sodium hydroxide in certain amount are added to maintain certain glycerin concentration. The present invention has the advantages of lowered investment and power consumption, raised final PDO concentration, raised production strength and increased bacteria biomass. |
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PCT： |
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