Fusion protein capable of removing HPV E7 protein and its encoding gene and application |
Title: |
Fusion protein capable of removing HPV E7 protein and its encoding gene and application |
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Application Number: |
200710117817 |
Application Date: |
2007/06/25 |
Announcement Date: |
2008/01/09 |
Pub. Date: |
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Publication Number: |
101100487 |
Announcement Number: |
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Grant Date: |
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Granted Pub. Date: |
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ApplicationType: |
Invention |
State/Country: |
94[China|shenzhen] |
IPC: |
C07K 19/00C12N 15/62A61K 38/16A61K 48/00A61P 35/00 |
Applicant(s): |
Graduate School at Shenzhen, Tsinghua University |
Inventor(s): |
Ji Yanhong, Zhang Yaou |
Key Words: |
Fusion protein, encoding gene, application, HPV E7 protein |
Abstract: |
A fusion protein for eliminating HPV E7 protein, its encoding gene and its use are disclosed. The fusion protein contains (1) or (2) protein, human F-box protein structural domain and human RB protein A-B box structural domain. The process is carried out by: substituting fusion protein amino-acid residue sequence with one or multi-amino acid residues and/or losing and/or adding, and eliminating protein derived from (1) in HPV E7. The fusion protein and/or the fusion-protein encoding gene, and/or recombinant expression carrier containing fusion protein encoding gene can be used to eliminate HPV E7 protein, prepare medicines in prevention and/or treatment HPV infection. |
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Relevancy information |
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Last Update |
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2008-4-17 |
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Selected patents owned by Tsinghua University filed in 2005 are loaded. |
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2008-3-31 |
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Selected patents owned by Tsinghua University filed in 2006 and 2007 are load. |
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