Method of preparing oil-phase oral insulin preparation |
Title: |
Method of preparing oil-phase oral insulin preparation |
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Application Number: |
01115327 |
Application Date: |
2001/04/20 |
Announcement Date: |
2001/10/24 |
Pub. Date: |
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Publication Number: |
1318416 |
Announcement Number: |
1160122 |
Grant Date: |
2004-8-4 |
Granted Pub. Date: |
2004-8-4 |
ApplicationType: |
Invention |
State/Country: |
11[China|beijing] |
IPC: |
A61K 9/00, A61K 38/28, A61P 3/10 |
Applicant(s): |
Qinghua Univ. |
Inventor(s): |
Zheng Changxue, Duan Mingxing, Ma Hong |
Key Words: |
oil-phase, oral, insulin preparation |
Abstract: |
The present invention relates to the field of preparing biological medicine and the oil-phase oral insulin preparation is prepared by the processes of dissolving certain amount of insulin in acid water phase buffering solution A; adding the buffering solution A into non-ionic surfactant solution with hydrophilic lipophilic balance value HLB between 10 and 20 via stirring to form solution B; and adding the solution B into liquid oil phase or emulsifier with hydrophilic lipophilic balance value HLB between 0 and 20 via stirring to form the oil phase preparation. The present invention has the features of simple preparation process and low cost and after oral taking, the preparation can resist the degradation effect of gastrointestinal enzyme and is easy to absorb to produce hypoglycemic effect. |
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Relevancy information |
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Last Update |
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2008-4-17 |
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Selected patents owned by Tsinghua University filed in 2005 are loaded. |
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2008-3-31 |
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Selected patents owned by Tsinghua University filed in 2006 and 2007 are load. |
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