Method for preparing screening spare library of natural product mixture medicament such as Chinese traditional medicine and application thereof
Title:
Method for preparing screening spare library of natural product mixture medicament such as Chinese traditional medicine and application thereof
Application Number:
200710064730
Application Date:
2007/03/23
Announcement Date:
2008/01/16
Pub. Date:
Publication Number:
101104955
Announcement Number:
Grant Date:
Granted Pub. Date:
ApplicationType:
Invention
State/Country:
12[China|tianjin]
IPC:
C40B 40/04, C40B 50/00, C40B 30/04
Applicant(s):
Nankai University
Inventor(s):
Rao Zihe, Lou Zhiyong, Sun Yuna, Ma Ming
Key Words:
screening spare library, natural product, mixture medicament, Chinese traditional medicine
Abstract:
The invention provides a preparation method of secondary metabolite mixture drug screening library for the drug screening based on protein crystal structure and the use of the drug screening library for screening drugs based on protein crystal structure. The preparation method is high in efficiency, rapid, accurate, reliable and practicable. By optimizing the raw medicines, the method avoids interference components and retains other components of the raw medicine. The inventive drug screening library helps to rapidly obtain a refined three-dimensional structure of a composite of target molecule and target protein.
Claim:
Priority:
PCT:
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