Small molecular inhibiting agent for coronavirus main proteinase, its preparation method and uses
Title：
Small molecular inhibiting agent for coronavirus main proteinase, its preparation method and uses
Application Number：
 200410087721
Application Date：
 2004/10/22
Announcement Date：
 2006/04/26
Pub. Date：
Publication Number：
 1763002
Announcement Number：
Grant Date：
Granted Pub. Date：
ApplicationType：
 Invention
State/Country：
 11[China|beijing]
IPC：
 C07D207/26, C07D413/12, A61K 31/40, A61K 31/42, A61P 31/14, A61P 11/00
Applicant(s)：
 Tsinghua University
Inventor(s)：
 Rao Zihe, Yang Haitao, Xue Xiaoyu, Yang Kailin, Mark Bartram, Ma Dawei, Xie Weiqing
Key Words：
 Small molecular inhibiting agent, coronavirus, main proteinase, preparation method, uses
Abstract：
 The present invention is serial small molecular inhibitor designed based on the crystal structure of main proteinase of SARS coronavirus and in the structural general expression as shown. The present invention also provides the preparation process of the small molecular inhibitor and its use in preparing medicine for preventing and treating various kinds of coronavirus infection.
Claim：
Priority：
PCT：
LegalStatus：

Recommend this patent:
1 2 3 4 5
Average ( 0 votes):
                                                                          Recommended Patents>>

Relevancy information

Method for screening SARS coronaviruses main Protease inhibitors from natural product such as Chinese medicinal materials mixture prepared storeroom
Alkylcyclohexyl multiple-fluorine biphenyl derivative and its preparation method and uses
Dphenylacetylene derivative and its preparation method and uses


Other Patents of Same Inventor

Method for screening SARS coronaviruses main Protease inhibitors from natural product such as Chinese medicinal materials mixture prepared storeroom
New method for screening HCV-NS5B protein inhibitor from Chinese herb medicines natural products mixture alternate library
Novel methods for high efficiency and rapid getting fine three dimensional structure of target protein composite body and target molecule
Method for preparing screening spare library of natural product mixture medicament such as Chinese traditional medicine and application thereof
Expression vector based on coronavirus proteolytic cleavage and its application



News & Events More>>

Last Update  
2008-4-17
  Selected patents owned by Tsinghua University filed in 2005 are loaded.
2008-3-31
  Selected patents owned by Tsinghua University filed in 2006 and 2007 are load.







Copyright 2008-2015 All Rights Reserved Patent License of China.      Designed by Easygo