3D controlled stacking formation method of cell-material units |
Title： |
| 3D controlled stacking formation method of cell-material units |
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Application Number： |
200410009787 |
Application Date： |
2004/11/12 |
Announcement Date： |
2005/04/27 |
Pub. Date： |
2006/08/02 |
Publication Number： |
1609210 |
Announcement Number： |
1267549 |
Grant Date： |
2006-8-2 |
Granted Pub. Date： |
2006-8-2 |
ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
C12N 11/04, C12N 5/08 |
Applicant(s)： |
Tsinghua Univ. |
Inventor(s)： |
Yan Yongnian, Xiong Zhuo, Wang Xiaohong |
Key Words： |
3D, controlled stacking, formation method, cell-material units |
Abstract： |
The present invention is 3D controlled stacking formation method of cell-material units. Ion concentration sensitive material and cell tactophily promoting biodegradable material(s) are first prepared into aqua and sterilized; one or several kinds of cell are then mixed with the solution to form cell-material solution mixture; and various kinds of cell-material solution mixture are extruded or jetted in preset structure and path to form cell-material units stacked in different spatial positions, to form cell-material gel with certain configuration and strength in corresponding triggering condition, and to obtain tissue organ rudiment via stacking. The present invention is based on the basic dispersion/stacking principle for fast formation to realize the accurate locating and formation of one or several kinds of cell in 3D space without damaging cell and other live biological body. The present invention is favorable to cell amplification and differentiation. |
Claim： |
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Priority： |
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PCT： |
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LegalStatus： |
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