Water gel fast forming process based on bionic process |
Title： |
| Water gel fast forming process based on bionic process |
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Application Number： |
200610011550 |
Application Date： |
2006/03/24 |
Announcement Date： |
2006/08/23 |
Pub. Date： |
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Publication Number： |
1820791 |
Announcement Number： |
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Grant Date： |
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Granted Pub. Date： |
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ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
A61L 27/52, A61L 27/40 |
Applicant(s)： |
Tsinghua Univ. |
Inventor(s)： |
Xiong Zhuo, Yang Yongnian, Li Shengjie, Wang Xiaohong, Wu Rendong, Lin Feng, Zhang Renji,Lu Qingping |
Key Words： |
Water gel, fast forming, bionic process |
Abstract： |
The fast bionic water gel forming process simulates human blood coagulation process to produce fibrin gel. Fibrinogen and medical water soluble polymer material, as well as thrombin, Ca ion and blood coagulation factor are prepared into two multiple-component water solutions and the two water solutions are made to mix and accumulate in certain spatial position by means of digital micro dropping and jetting technology while producing enzyme reaction to form water gel with fibrin as matrix, so as to make 3D water gel structure with complicated spatial shape and porous structure. The coagulation process has complicated and effective regulating and controlling mechanism, and the water gel structure has excellent mechanical and biological performance, stable structure and effectively regulated degradation speed. The present invention is suitable for forming tissue engineering sample, medicine slow releasing carrier, etc. |
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PCT： |
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