Reagent for separating amino acid enantiomer
Title：
Reagent for separating amino acid enantiomer
Application Number：
 200510011173
Application Date：
 2005/01/14
Announcement Date：
 2005/09/21
Pub. Date：
 2007/08/22
Publication Number：
 1670012
Announcement Number：
 1332934
Grant Date：
 2007-8-22
Granted Pub. Date：
 2007-8-22
ApplicationType：
 Invention
State/Country：
 11[China|beijing]
IPC：
 C07C 227/40, B01D 11/00
Applicant(s)：
 Tsinghua University
Inventor(s)：
 Tan Bin, Luo Guangsheng, Wang Jiading
Key Words：
 amino acid, enantiomer, separate, reagent
Abstract：
 The invention relates to a new pattern agent for separating amino acid enantiomer, which belongs to the mass transfer isolation technique field about chemical industry, chemical and medicine. The invention discloses the new pattern agent to solve the problem which both the low selective and small flux of chiral selectors hinder the chirality enantiomer drugs industrial mass production seriously, which comprises: mixing the chirality molecule D-dimethylbenzoyl tartaric acid or L-dimethylbenzoyl tartaric acid with the mole ratio as 1:1-40 and D2EHPA, adding octanol as deflocculating agents, and stirring to get the D-dimethylbenzoyl tartaric acid, L-dimethylbenzoyl tartaric acid or D2EHPA with unreactive chiral molecules and the mixture liquid system of intermediate complex compound from the reaction formation. The mixture liquid system is the said new pattern agent for separating amino acid enantiomer.
Claim：
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