Prepn of osteological material containing nano phase calcium phosphate, collagen and alginate |
Title： |
| Prepn of osteological material containing nano phase calcium phosphate, collagen and alginate |
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Application Number： |
01141901 |
Application Date： |
2001/09/21 |
Announcement Date： |
2002/02/27 |
Pub. Date： |
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Publication Number： |
1337271 |
Announcement Number： |
1157232 |
Grant Date： |
2004-7-14 |
Granted Pub. Date： |
2004-7-14 |
ApplicationType： |
Invention |
State/Country： |
11[China|beijing] |
IPC： |
A61F 2/28, A61K 38/39, A61L 27/44, A61L 27/56 |
Applicant(s)： |
Qinghua Univ. |
Inventor(s)： |
Cui Fuzhai, Zhang Shuming, Liao Susan |
Key Words： |
osteological material, nano phase, calcium phosphate, collagen, alginate |
Abstract： |
The preparation method of bone material containing nanometer phase calcium phosphorus salt, collagen and aliginate includes the following steps: slowly drop-adding solution containing calcium iron into acid-soluble collagen solution, then slowly drop-adding aqueous solution containing phosphoric acid radical ion into said solution while stirring, and slowly drop-adding alkali liquor to regulate pH value while stirring, standing still and removing supernatant fluid, centrifugal separation, precipitation, grinding to obtain dried powder, mixing the dried powder with sodium alginate and water to obtain a product, placing said product into mould, forming, demoulding, soaking in distilled water, drying to obtain the invented bone material with excellent biological compatibility and imitation bone property in structure, reasonable strengthen and void volume. Said invented bone material can be used as implanted degradable bone material. |
Claim： |
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Priority： |
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PCT： |
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LegalStatus： |
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