Method and system for detecting biological chip by space phase modulation interference array
Title：
Method and system for detecting biological chip by space phase modulation interference array
Application Number：
 200410057323
Application Date：
 2004/08/27
Announcement Date：
 2005/03/02
Pub. Date：
 2007/04/25
Publication Number：
 1588064
Announcement Number：
 1312476
Grant Date：
 2007-4-25
Granted Pub. Date：
 2007-4-25
ApplicationType：
 Invention
State/Country：
 11[China|beijing]
IPC：
 G01N 33/50, G01N 21/25
Applicant(s)：
 Tsing Univ.
Inventor(s)：
 Yu Xinglong, Wang Dingxin, Wei Xing
Key Words：
 Method, system, detect, biological chip, space phase, modulation interference array
Abstract：
 The invention relates to a method and system of adopting space phase modulation and interference array to detect the biochip, which belongs to biological technical field. The invention aims to overcome the deficiency of current technique and provides a new biochip detecting method and system, which can detect different volumes of DAN chips and protein chips dispense with mark and real-time achieve the information about the interaction of the biomolecules. The principle of the detection by space phase modulation and interference array is: the light reflected by the biosensor unit entering wallaston prism after combined by the one dimensional magnifying lens, the contained s ray and p ray which is polarizationdirection is divided into the two rays transmitting in different direction and realizing co-lightpath space phase modulation and interference in wallaston prism; the interference fringe being converted into electrical signal through the polarizer and imaging lens, the information of real-time phase change of the each unit on the array chip being acquired after processing and be offered to the biologist and medical scientists to parse.
Claim：
Priority：
PCT：
LegalStatus：

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2008-4-17
  Selected patents owned by Tsinghua University filed in 2005 are loaded.
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