Mineralized fibrion/macromolecule composite porous material and preparation method
Title:
Mineralized fibrion/macromolecule composite porous material and preparation method
Application Number:
200410003454
Application Date:
2004/03/19
Announcement Date:
2005/01/12
Pub. Date:
2006/07/26
Publication Number:
1562389
Announcement Number:
1265847
Grant Date:
2006-7-26
Granted Pub. Date:
2006-7-26
ApplicationType:
Invention
State/Country:
11[China|beijing]
IPC:
A61L 27/44
Applicant(s):
Tsinghua Univ.
Inventor(s):
Cui Fuzhai, Kong Xiangdong, Zhang Wei
Key Words:
Mineralized fibrion, macromolecule, composite porous material, preparation method
Abstract:
A mineralized porous silk protein/high-molecular material composition with high biocompatibility and biodegradability for repairing bone is prepared through preparing the aqueous solution of deglued silk protein, dropping the Ca ions contained solution in it while stirring, slowly dropping PO4 ions contained solution, regulating pH value, stirring, laying aside, centrifugal separation and washing several times, vacuum drying, grinding, and mixing with the biocompatible high-molecular material chosen from polylactic acid, copolymer of lactic acid and hydroxy acetic acid, sodium alginate, etc.
Claim:
Priority:
PCT:
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