Derivative of vibothymidine and its preparation process and application
Title:
Derivative of vibothymidine and its preparation process and application
Application Number:
200410006164
Application Date:
2004/03/04
Announcement Date:
2005/01/05
Pub. Date:
2007/03/14
Publication Number:
1560064
Announcement Number:
1304408
Grant Date:
2007-3-14
Granted Pub. Date:
2007-3-14
ApplicationType:
Invention
State/Country:
11[China|beijing]
IPC:
C07H 19/06, A61K 31/707, A61P 35/00, A61P 31/18
Applicant(s):
Tsinghua Univ.
Inventor(s):
Zhao Yufen, Sun Xiaobin, Qiao Renzhong
Key Words:
Derivative, vibothymidine, preparation process, application
Abstract:
The invention discloses a thymine nucleoside derivative and its preparing method and its application, a compound which can be 3'-azidothymidine-5'-phosphorylated(N-methyl imidazole-2- formyl alkyl diamine) cyclohexyl ester and 2', 3'-dehydro and deoxy thymidine-5'-phsporylated (N-methyl imidazole-2- formyl alkyl diamine). It also provides its preparing method. The derivative is a candidate premedical compound with the effects of antivirus, antitumor and anti AIDS virus.
Claim:
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PCT:
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