Breviscapinum long-circulating nanoliposome and its preparation method |
Title: |
Breviscapinum long-circulating nanoliposome and its preparation method |
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Application Number: |
200510063206 |
Application Date: |
2005/04/06 |
Announcement Date: |
2006/10/11 |
Pub. Date: |
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Publication Number: |
1843368 |
Announcement Number: |
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Grant Date: |
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Granted Pub. Date: |
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ApplicationType: |
Invention |
State/Country: |
11[China|beijing] |
IPC: |
A61K 31/7048, A61K 9/127, A61P 9/00 |
Applicant(s): |
Tsinghua University |
Inventor(s): |
Luo Guoan, Tian Weiwei, Liu Qingfei, Wang Yiming, Hu Xinzhou |
Key Words: |
Breviscapinum, long-circulating, nanoliposome, preparation method |
Abstract: |
The invention discloses a breviscapinum long-circulating nanoliposome and its preparation method, wherein the constituents include breviscapine, phosphatide, polyethylene glycol derived phosphatide (PEG2000-DSPE) and cholestrin by a molar ratio of 55:25-55:3-7:2.2-18.3, the dose type of the medicinal preparation includes injections, freeze-dried powder injections and sprays. The phospholipids can be soya bean lecithin, yolk phosphatidy icholine, hydrogenated soya bean lecithin, hydrogenated yolk lecithin, di-palmityl phosphatidyl choline or DPOG. |
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